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Home » Topics » Herd Health » Vaccination

Vaccination
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ARTICLES

Modified-live versus killed vaccines: What are the differences?

The risk for disease in cattle depends on many factors. How a vaccine is selected depends on factors that include what organism we wish to vaccinate against.
September 25, 2025
Richard Linhart

Cattle vaccines are generally available in one of two different forms, either modified-live or attenuated products, or killed or inactivated products. Each type of vaccine has its unique properties, advantages and disadvantages, and its place in a herd health program.


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Is salmonella present on your dairy?

Producers should work with their veterinarian to develop and implement routine biosecurity, monitoring and preventative practices, like vaccination, to help control salmonellosis on their farm.
July 8, 2025
Angela Rowson

Cows infected with salmonella can shed organisms in their manure, colostrum, saliva, milk and vaginal and nasal secretions. The disease is commonly spread from one cow to another when she consumes the manure of an animal that is shedding the bacteria. Cows usually ingest this infected manure in their feed or water. 


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Preventing vaccine failures

Proper nutrition, reduced stress and strategic scheduling are essential for effective immunization.
June 19, 2025
Chris Chase

Most “vaccine failures” are not due to the vaccine itself but to the animal’s immune system not being ready – often due to poor timing. The immune system’s job isn’t to prevent disease but to maintain health, which requires appropriate management, sound nutrition, low stress, biosecurity and a well-planned vaccine program. 


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Immunity: More than a vaccine

Vaccines aid cow immunity, but full immune health relies on trace minerals like zinc, copper and selenium. Proper supplementation enhances disease resistance and vaccine effectiveness.
May 27, 2025
Craig J. Louder

While vaccines contribute greatly to a cow’s immune system, there are other aspects of the immune system that should not be forgotten. Ensuring that essential elements such as trace minerals are provided, allows for the cow’s entire immune system to be ready to fight off an invasion, not just relying on the special forces.


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When pinkeye vaccines fail

Pinkeye can be a challenge in cattle; however, vaccination, environmental management and custom vaccines can help to effectively prevent and treat the disease. Additional factors can influence your vaccine effectiveness.
May 5, 2025
Jason Shumaker

Pinkeye in cattle presents a significant challenge for producers, impacting animal performance and requiring costly and time-consuming treatments. Vaccination against pinkeye is crucial in a producer's prevention strategy, alongside effective fly, weed and dust control with appropriate trace mineral supplementation.


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Vaccine-adverse reactions: How to minimize the lumps and bumps

Vaccinations are meant to help prevent and treat disease. However, adverse reactions can range in severity from mild temporary lumps and bumps to sudden systemic anaphylactic shock with fluid accumulation in the lungs and death.
May 10, 2024
Richard Linhart

Vaccine products that are administered to cattle are foreign to the animal’s body. The goal is for the body to recognize these foreign organisms and develop an immune response for protection in the event of a future disease challenge.


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Vaccination protocols: Maximizing vaccine efficacy

Vaccines should be used as a management tool to bolster the special forces of the adaptive immune system.
March 13, 2024
Craig J. Louder

The immune system is the body’s military. It is tasked with being able to recognize pathogenic invaders that have entered the body and eliminate them as quickly as possible.


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A guide to get the best ROI from calf vaccination

October 5, 2023
Jonathan Townsend

Understanding the fundamentals of vaccination helps optimize the return on your vaccine investments and ensure calves are prepared for the challenges they’ll face.


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BRD prevention in dairy calves starts with dry cow management

Proper dry cow management practices are paramount for calf health, growth and early immunity.
October 4, 2023
David L. Prentice

Managing bovine respiratory disease (BRD) can sometimes feel like a game of whack-a-mole for dairy producers. Many stressors can pop up with little to no advanced warning early in a calf’s life, putting them at greater risk for developing BRD.  


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Animal agriculture awaits ‘normal accidents’ when it comes to biosecurity

Routinely administering a vaccine against any strain secures the production capacity and logistics needed to deliver a correctly targeted vaccine quickly when the need arises.
June 20, 2023
Julie Smith

John Law published a paper in 2006 in the journal Environment and Planning about the situation “developed” countries of the world find themselves in. They are precariously vulnerable to an incursion of a fast-moving animal disease that exists elsewhere in the world.


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